| 论文作者 |
Yang, WC; Zhou, PC; Xia, RQ; Dong, HY; Wang, X; Ma, H; Gao, X; Zong, G |
| 摘要 |
Aims Current guidelines recommend >= 150 weekly minutes of moderate-to-vigorous physical activity (MVPA) for health, but how activity patterns affect outcomes is unclear. This study examined whether the 'weekend warrior' (WW) pattern (i.e. most MVPA achieved over 1-2 days) was associated with a similar risk of incident cardiovascular disease (CVD) events as regular activity (RA) in adults with diabetes, using UK Biobank data.Methods and results Physical activity was assessed via wrist-worn accelerometers and questionnaires. Participants were grouped by MVPA pattern and duration: WWs, RA, or inactive. Cox regression models estimated hazard ratios (HRs) and 95% CIs for associations between physical activity patterns and CVD incidence. Among 3061 participants with diabetes [mean (SD) age, 65.0 (7.1) years; 59.6% men], accelerometer-measured physical activity patterns were classified as WW (n = 976), RA (n = 503), and inactive (n = 1582). During a median follow-up of 6.6 years, a total of 254 (8.3%) incident CVD cases were identified. Compared with the inactive group, the multivariable-adjusted HRs for incident CVD in the RA and WW groups were 0.60 (95% CI: 0.39, 0.90) and 0.50 (95% CI: 0.35, 0.71), respectively. A comparison of WW vs. RA for CVD risk showed no significant difference in the multivariable-adjusted HR of 0.85 (95% CI: 0.54, 1.34, P = 0.50). Similar results were found in an additional analysis of 16 503 participants whose physical activity data were obtained via a questionnaire.Conclusion This study shows that among participants with diabetes, WWs have a CVD risk similar to that of RA individuals, compared with inactive individuals. This study investigates the influence of the weekend warrior (WW) physical activity pattern, characterized by the accumulation of the majority of weekly moderate-to-vigorous physical activity (MVPA) within 1-2 days, on cardiovascular disease risk in individuals with diabetes, in comparison to regular activity (where most MVPA is distributed over more than 2 days) and inactivity.In individuals with diabetes, the WW physical activity pattern is associated with a lower cardiovascular risk than that observed in inactive individuals and a comparable risk to that of those engaging in regular activity.This WW pattern presents a feasible approach for individuals with diabetes to adhere to the recommended weekly MVPA guidelines, thereby resolving the prior uncertainty regarding its effects in this population. |
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